What are first-generation antipsychotic medications commonly referred to as?

First-generation antipsychotic medications are commonly referred to as typical or neuroleptic antipsychotics. This terminology is rooted in the history of antipsychotic medications. These medications were developed in the mid-20th century, primarily for the treatment of psychosis, particularly schizophrenia. The term "typical" is used to denote their standard characteristics and effects, while "neuroleptic" highlights their action of suppressing or reducing the symptoms of psychosis through impacts on the nervous system.

In this context, these medications primarily work by blocking dopamine receptors in the brain, which helps to alleviate positive symptoms of schizophrenia, such as hallucinations and delusions. Understanding this classification is significant for anyone involved in mental health care, as it helps differentiate between various types of antipsychotic medications and their respective uses, side effects, and mechanisms of action.

The other terms listed do not accurately reflect first-generation antipsychotics. "Atypical antipsychotics" refers to the newer class of medications that emerged later and tend to have a broader spectrum of activity and side effect profile. "Tetracycline antipsychotics" and "novel antipsychotics" are not commonly recognized terms associated with first-generation